Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity

Hypoxia contributes to airway inflammation and remodeling in several lung diseases; however, exactly how hypoxic pulmonary epithelium regulates allergic inflammation remains to be fully characterized. Here, we report that conditional deletion of the E3 ubiquitin ligase VHL in lung epithelial cells r...

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Detalles Bibliográficos
Autores principales: Han, Jihye, Wan, Qingqing, Seo, Goo-Young, Kim, Kenneth, el Baghdady, Sarah, Lee, Jee H., Kronenberg, Mitchell, Liu, Yun-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093746/
https://www.ncbi.nlm.nih.gov/pubmed/35532553
http://dx.doi.org/10.1084/jem.20211985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093746/
https://www.ncbi.nlm.nih.gov/pubmed/35532553
http://dx.doi.org/10.1084/jem.20211985

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