Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation

Translocation of Fibroblast Growth Factor Receptors (FGFRs) often leads to aberrant cell proliferation and cancer. The BCR-FGFR1 fusion protein, created by chromosomal translocation t(8;22)(p11;q11), contains Breakpoint Cluster Region (BCR) joined to Fibroblast Growth Factor Receptor 1 (FGFR1). BCR-...

Descripción completa

Detalles Bibliográficos
Autores principales: Peiris, Malalage N., Meyer, April N., Warda, Dalida, Campos, Alexandre Rosa, Donoghue, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093983/
https://www.ncbi.nlm.nih.gov/pubmed/35574218
http://dx.doi.org/10.18632/oncotarget.28228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093983/
https://www.ncbi.nlm.nih.gov/pubmed/35574218
http://dx.doi.org/10.18632/oncotarget.28228

Ejemplares similares