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Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation

Translocation of Fibroblast Growth Factor Receptors (FGFRs) often leads to aberrant cell proliferation and cancer. The BCR-FGFR1 fusion protein, created by chromosomal translocation t(8;22)(p11;q11), contains Breakpoint Cluster Region (BCR) joined to Fibroblast Growth Factor Receptor 1 (FGFR1). BCR-...

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Detalles Bibliográficos
Autores principales:	Peiris, Malalage N., Meyer, April N., Warda, Dalida, Campos, Alexandre Rosa, Donoghue, Daniel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093983/ https://www.ncbi.nlm.nih.gov/pubmed/35574218 http://dx.doi.org/10.18632/oncotarget.28228

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