Genome-wide analysis of methylation in rat fetal heart under hyperglycemia by methylation-dependent restriction site–associated DNA sequencing

Diabetes mellitus causes an increased incidence of congenital heart malformations. However, the pathogenesis and potential epigenetic mechanism involved in this process are unclear. In this study, we used MethylRAD sequencing to compare changes in methylation levels in the genomic landscapes in the...

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Detalles Bibliográficos
Autores principales: Meng, Rui, Song, Junxian, Guan, Lina, Li, Qian, Shi, Cuige, Su, Dongmei, Ma, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094537/
https://www.ncbi.nlm.nih.gov/pubmed/35544480
http://dx.doi.org/10.1371/journal.pone.0268117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094537/
https://www.ncbi.nlm.nih.gov/pubmed/35544480
http://dx.doi.org/10.1371/journal.pone.0268117

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