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Neuroprotective role of nitric oxide inhalation and nitrite in a Neonatal Rat Model of Hypoxic-Ischemic Injury

BACKGROUND: There is evidence from various models of hypoxic-ischemic injury (HII) that nitric oxide (NO) is protective. We hypothesized that either inhaled NO (iNO) or nitrite would alleviate brain injury in neonatal HII via modulation of mitochondrial function. METHODS: We tested the effects of iN...

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Detalles Bibliográficos
Autores principales: Jung, Peter, Ha, Euntaik, Zhang, Meijuan, Fall, Carolyn, Hwang, Mindy, Taylor, Emily, Stetkevich, Samuel, Bhanot, Aditi, Wilson, Christopher G., Figueroa, Johnny D., Obenaus, Andre, Bragg, Shannon, Tone, Beatriz, Eliamani, Saburi, Holshouser, Barbara, Blood, Arlin B., Liu, Taiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094545/
https://www.ncbi.nlm.nih.gov/pubmed/35544542
http://dx.doi.org/10.1371/journal.pone.0268282