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Comparison of the Toponomes of Alveolar Macrophages From Wild Type and Surfactant Protein A Knockout Mice and Their Response to Infection

BACKGROUND: Surfactant protein-A (SP-A) plays a critical role in lung innate immunity by regulating alveolar macrophages (AM), expression of inflammatory mediators, and other host defense proteins. The toponome imaging system (TIS), a serial immunostainer, was used to study the AM toponome because i...

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Detalles Bibliográficos
Autores principales: Phelps, David S., Chinchilli, Vernon M., Zhang, Xuesheng, Shearer, Debra, Weisz, Judith, Floros, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094576/
https://www.ncbi.nlm.nih.gov/pubmed/35572576
http://dx.doi.org/10.3389/fimmu.2022.853611