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Regulation of developmental hierarchy in Drosophila neural stem cell tumors by COMPASS and Polycomb complexes

COMPASS and Polycomb complexes are antagonistic chromatin complexes that are frequently inactivated in cancers, but how these events affect the cellular hierarchy, composition, and growth of tumors is unclear. These characteristics can be systematically investigated in Drosophila neuroblast tumors i...

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Detalles Bibliográficos
Autores principales: Gaultier, Cassandra, Foppolo, Sophie, Maurange, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094666/
https://www.ncbi.nlm.nih.gov/pubmed/35544555
http://dx.doi.org/10.1126/sciadv.abi4529