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Autophagic LC3(+) calcified extracellular vesicles initiate cartilage calcification in osteoarthritis

Pathological cartilage calcification plays an important role in osteoarthritis progression but in which the origin of calcified extracellular vesicles (EVs) and their effects remain unknown. Here, we demonstrate that pathological cartilage calcification occurs in the early stage of the osteoarthriti...

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Detalles Bibliográficos
Autores principales: Yan, Jianfei, Shen, Minjuan, Sui, Bingdong, Lu, Weicheng, Han, Xiaoxiao, Wan, Qianqian, Liu, Yingying, Kang, Junjun, Qin, Wenpin, Zhang, Zibing, Chen, Da, Cao, Yuan, Ying, Siqi, Tay, Franklin R., Niu, Li-na, Jiao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094669/
https://www.ncbi.nlm.nih.gov/pubmed/35544558
http://dx.doi.org/10.1126/sciadv.abn1556