Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

Human myelin disorders are commonly studied in mouse models. Since both clades evolutionarily diverged approximately 85 million years ago, it is critical to know to what extent the myelin protein composition has remained similar. Here, we use quantitative proteomics to analyze myelin purified from h...

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Detalles Bibliográficos
Autores principales: Gargareta, Vasiliki-Ilya, Reuschenbach, Josefine, Siems, Sophie B, Sun, Ting, Piepkorn, Lars, Mangana, Carolina, Späte, Erik, Goebbels, Sandra, Huitinga, Inge, Möbius, Wiebke, Nave, Klaus-Armin, Jahn, Olaf, Werner, Hauke B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094742/
https://www.ncbi.nlm.nih.gov/pubmed/35543322
http://dx.doi.org/10.7554/eLife.77019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094742/
https://www.ncbi.nlm.nih.gov/pubmed/35543322
http://dx.doi.org/10.7554/eLife.77019

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