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Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice
Human myelin disorders are commonly studied in mouse models. Since both clades evolutionarily diverged approximately 85 million years ago, it is critical to know to what extent the myelin protein composition has remained similar. Here, we use quantitative proteomics to analyze myelin purified from h...
Autores principales: | Gargareta, Vasiliki-Ilya, Reuschenbach, Josefine, Siems, Sophie B, Sun, Ting, Piepkorn, Lars, Mangana, Carolina, Späte, Erik, Goebbels, Sandra, Huitinga, Inge, Möbius, Wiebke, Nave, Klaus-Armin, Jahn, Olaf, Werner, Hauke B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094742/ https://www.ncbi.nlm.nih.gov/pubmed/35543322 http://dx.doi.org/10.7554/eLife.77019 |
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