METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis

Methyltransferase-like 3 (METTL3) and N(6)-methyladenosine (m(6)A) are involved in many types of biological and pathological processes, including DNA repair. However, the function and mechanism of METTL3 in DNA repair and chemotherapeutic response remain largely unknown. In present study, we identif...

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Detalles Bibliográficos
Autores principales: Li, Enjie, Xia, Mingyue, Du, Yu, Long, Kaili, Ji, Feng, Pan, Feiyan, He, Lingfeng, Hu, Zhigang, Guo, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094751/
https://www.ncbi.nlm.nih.gov/pubmed/35502895
http://dx.doi.org/10.7554/eLife.75231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094751/
https://www.ncbi.nlm.nih.gov/pubmed/35502895
http://dx.doi.org/10.7554/eLife.75231

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