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METTL3 promotes homologous recombination repair and modulates chemotherapeutic response in breast cancer by regulating the EGF/RAD51 axis
Methyltransferase-like 3 (METTL3) and N(6)-methyladenosine (m(6)A) are involved in many types of biological and pathological processes, including DNA repair. However, the function and mechanism of METTL3 in DNA repair and chemotherapeutic response remain largely unknown. In present study, we identif...
Autores principales: | Li, Enjie, Xia, Mingyue, Du, Yu, Long, Kaili, Ji, Feng, Pan, Feiyan, He, Lingfeng, Hu, Zhigang, Guo, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9094751/ https://www.ncbi.nlm.nih.gov/pubmed/35502895 http://dx.doi.org/10.7554/eLife.75231 |
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