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Cecal Patches Generate Abundant IgG2b-Bearing B Cells That Are Reactive to Commensal Microbiota

Gut-associated lymphoid tissue (GALT), such as Peyer's patches (PPs), are key inductive sites that generate IgA(+) B cells, mainly through germinal center (GC) responses. The generation of IgA(+) B cells is promoted by the presence of gut microbiota and dietary antigens. However, the function o...

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Detalles Bibliográficos
Autores principales: Tsuda, Masato, Okada, Hiraku, Kojima, Natsuki, Ishihama, Fumiya, Muraki, Yuhei, Oguma, Toshiki, Hattori, Nanako, Mizoguchi, Takumi, Mori, Kiyoaki, Hachimura, Satoshi, Takahashi, Yoshimasa, Takahashi, Kyoko, Kaminogawa, Shuichi, Hosono, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095398/
https://www.ncbi.nlm.nih.gov/pubmed/35571567
http://dx.doi.org/10.1155/2022/3974141