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Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system

Antidepressants are an effective treatment for major depressive disorder (MDD), although individual response is unpredictable and highly variable. Whilst the mode of action of antidepressants is incompletely understood, many medications are associated with changes in DNA methylation in genes that ar...

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Detalles Bibliográficos
Autores principales: Barbu, Miruna C., Huider, Floris, Campbell, Archie, Amador, Carmen, Adams, Mark J., Lynall, Mary-Ellen, Howard, David M., Walker, Rosie M., Morris, Stewart W., Van Dongen, Jenny, Porteous, David J., Evans, Kathryn L., Bullmore, Edward, Willemsen, Gonneke, Boomsma, Dorret I., Whalley, Heather C., McIntosh, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095457/
https://www.ncbi.nlm.nih.gov/pubmed/34880450
http://dx.doi.org/10.1038/s41380-021-01412-7