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Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system
Antidepressants are an effective treatment for major depressive disorder (MDD), although individual response is unpredictable and highly variable. Whilst the mode of action of antidepressants is incompletely understood, many medications are associated with changes in DNA methylation in genes that ar...
Autores principales: | Barbu, Miruna C., Huider, Floris, Campbell, Archie, Amador, Carmen, Adams, Mark J., Lynall, Mary-Ellen, Howard, David M., Walker, Rosie M., Morris, Stewart W., Van Dongen, Jenny, Porteous, David J., Evans, Kathryn L., Bullmore, Edward, Willemsen, Gonneke, Boomsma, Dorret I., Whalley, Heather C., McIntosh, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095457/ https://www.ncbi.nlm.nih.gov/pubmed/34880450 http://dx.doi.org/10.1038/s41380-021-01412-7 |
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