Cargando…

Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids

Due to an inability to ethically access developing human brain tissue as well as identify prospective cases, early-arising neurodevelopmental and cell-specific signatures of Schizophrenia (Scz) have remained unknown and thus undefined. To overcome these challenges, we utilized patient-derived induce...

Descripción completa

Detalles Bibliográficos
Autores principales: Notaras, Michael, Lodhi, Aiman, Dündar, Friederike, Collier, Paul, Sayles, Nicole M., Tilgner, Hagen, Greening, David, Colak, Dilek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095467/
https://www.ncbi.nlm.nih.gov/pubmed/34789849
http://dx.doi.org/10.1038/s41380-021-01316-6