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Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids
Due to an inability to ethically access developing human brain tissue as well as identify prospective cases, early-arising neurodevelopmental and cell-specific signatures of Schizophrenia (Scz) have remained unknown and thus undefined. To overcome these challenges, we utilized patient-derived induce...
Autores principales: | Notaras, Michael, Lodhi, Aiman, Dündar, Friederike, Collier, Paul, Sayles, Nicole M., Tilgner, Hagen, Greening, David, Colak, Dilek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095467/ https://www.ncbi.nlm.nih.gov/pubmed/34789849 http://dx.doi.org/10.1038/s41380-021-01316-6 |
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