Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine

(R,S)-ketamine elicits rapid-acting and sustained antidepressant actions in treatment-resistant patients with depression. (R)-ketamine produces longer-lasting antidepressant effects than (S)-ketamine in rodents; however, the precise molecular mechanisms underlying antidepressant actions of (R)-ketam...

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Detalles Bibliográficos
Autores principales: Yao, Wei, Cao, Qianqian, Luo, Shilin, He, Lujuan, Yang, Chun, Chen, Jiaxu, Qi, Qi, Hashimoto, Kenji, Zhang, Ji-chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095473/
https://www.ncbi.nlm.nih.gov/pubmed/34819637
http://dx.doi.org/10.1038/s41380-021-01377-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095473/
https://www.ncbi.nlm.nih.gov/pubmed/34819637
http://dx.doi.org/10.1038/s41380-021-01377-7

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