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Novel open reading frames in human accelerated regions and transposable elements reveal new leads to understand schizophrenia and bipolar disorder

Schizophrenia (SCZ) and bipolar disorder are debilitating neuropsychiatric disorders arising from a combination of environmental and genetic factors. Novel open reading frames (nORFs) are genomic loci that give rise to previously uncharacterized transcripts and protein products. In our previous work...

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Detalles Bibliográficos
Autores principales: Erady, Chaitanya, Amin, Krishna, Onilogbo, Temiloluwa O. A. E., Tomasik, Jakub, Jukes-Jones, Rebekah, Umrania, Yagnesh, Bahn, Sabine, Prabakaran, Sudhakaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095477/
https://www.ncbi.nlm.nih.gov/pubmed/34937870
http://dx.doi.org/10.1038/s41380-021-01405-6