Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance

Post-transcriptional modifications have critical roles in tRNA stability and function(1–4). In thermophiles, tRNAs are heavily modified to maintain their thermal stability under extreme growth temperatures(5,6). Here we identified 2′-phosphouridine (U(p)) at position 47 of tRNAs from thermophilic ar...

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Detalles Bibliográficos
Autores principales: Ohira, Takayuki, Minowa, Keiichi, Sugiyama, Kei, Yamashita, Seisuke, Sakaguchi, Yuriko, Miyauchi, Kenjyo, Noguchi, Ryo, Kaneko, Akira, Orita, Izumi, Fukui, Toshiaki, Tomita, Kozo, Suzuki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095486/
https://www.ncbi.nlm.nih.gov/pubmed/35477761
http://dx.doi.org/10.1038/s41586-022-04677-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095486/
https://www.ncbi.nlm.nih.gov/pubmed/35477761
http://dx.doi.org/10.1038/s41586-022-04677-2

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