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Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance
Post-transcriptional modifications have critical roles in tRNA stability and function(1–4). In thermophiles, tRNAs are heavily modified to maintain their thermal stability under extreme growth temperatures(5,6). Here we identified 2′-phosphouridine (U(p)) at position 47 of tRNAs from thermophilic ar...
Autores principales: | Ohira, Takayuki, Minowa, Keiichi, Sugiyama, Kei, Yamashita, Seisuke, Sakaguchi, Yuriko, Miyauchi, Kenjyo, Noguchi, Ryo, Kaneko, Akira, Orita, Izumi, Fukui, Toshiaki, Tomita, Kozo, Suzuki, Tsutomu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095486/ https://www.ncbi.nlm.nih.gov/pubmed/35477761 http://dx.doi.org/10.1038/s41586-022-04677-2 |
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