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Urolithin A attenuates auditory cell senescence by activating mitophagy

Aging of sensory organs is associated with a decline in mitochondrial function and the accumulation of dysfunctional mitochondria. Impaired mitophagy blocks the turnover of dysfunctional mitochondria and leads to their accumulation. Urolithin A (UA) induces mitophagy in various mammalian cells. This...

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Detalles Bibliográficos
Autores principales: Cho, Sung Il, Jo, Eu-Ri, Song, Hansoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095590/
https://www.ncbi.nlm.nih.gov/pubmed/35546176
http://dx.doi.org/10.1038/s41598-022-11894-2