PERSIST platform provides programmable RNA regulation using CRISPR endoRNases

Regulated transgene expression is an integral component of gene therapies, cell therapies and biomanufacturing. However, transcription factor-based regulation, upon which most applications are based, suffers from complications such as epigenetic silencing that limit expression longevity and reliabil...

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Detalles Bibliográficos
Autores principales: DiAndreth, Breanna, Wauford, Noreen, Hu, Eileen, Palacios, Sebastian, Weiss, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095627/
https://www.ncbi.nlm.nih.gov/pubmed/35562172
http://dx.doi.org/10.1038/s41467-022-30172-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095627/
https://www.ncbi.nlm.nih.gov/pubmed/35562172
http://dx.doi.org/10.1038/s41467-022-30172-3

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