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Supporting the gastrointestinal microenvironment during high-dose chemotherapy and stem cell transplantation by inhibiting IL-1 signaling with anakinra

High-dose chemotherapy causes intestinal inflammation and subsequent breakdown of the mucosal barrier, permitting translocation of enteric pathogens, clinically manifesting as fever. Antibiotics are mainstay for controlling these complications, however, they are increasingly recognized for their det...

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Detalles Bibliográficos
Autores principales: Wardill, H. R., de Mooij, C. E. M., Da Silva Ferreira, A. R., Havinga, H., Harmsen, H. J. M., van der Velden, W. J. F. M., van Groningen, L. F. J., Tissing, W. J. E., Blijlevens, N. M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095632/
https://www.ncbi.nlm.nih.gov/pubmed/35546555
http://dx.doi.org/10.1038/s41598-022-10700-3