Design, synthesis, and biological evaluation of a small molecule oral agonist of the glucagon-like-peptide-1 receptor

An absolute or relative deficiency of pancreatic β-cells mass and functionality is a crucial pathological feature common to type 1 diabetes mellitus and type 2 diabetes mellitus. Glucagon-like-peptide-1 receptor (GLP1R) agonists have been the focus of considerable research attention for their abilit...

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Detalles Bibliográficos
Autores principales: Girdhar, Khyati, Thakur, Shilpa, Gaur, Pankaj, Choubey, Abhinav, Dogra, Surbhi, Dehury, Budheswar, Kumar, Sunil, Biswas, Bidisha, Dwivedi, Durgesh Kumar, Ghosh, Subrata, Mondal, Prosenjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095748/
https://www.ncbi.nlm.nih.gov/pubmed/35378127
http://dx.doi.org/10.1016/j.jbc.2022.101889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095748/
https://www.ncbi.nlm.nih.gov/pubmed/35378127
http://dx.doi.org/10.1016/j.jbc.2022.101889

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