Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome

Fragile X Syndrome (FXS) is a monogenetic form of intellectual disability and autism in which well-established knockout (KO) animal models point to neuronal hyperexcitability and abnormal gamma-frequency physiology as a basis for key disorder features. Translating these findings into patients may id...

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Detalles Bibliográficos
Autores principales: Pedapati, Ernest V., Schmitt, Lauren M., Ethridge, Lauren E., Miyakoshi, Makoto, Sweeney, John A., Liu, Rui, Smith, Elizabeth, Shaffer, Rebecca C., Dominick, Kelli C., Gilbert, Donald L., Wu, Steve W., Horn, Paul S., Binder, Devin K., Lamy, Martine, Axford, Megan, Erickson, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095835/
https://www.ncbi.nlm.nih.gov/pubmed/35546357
http://dx.doi.org/10.1038/s42003-022-03395-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095835/
https://www.ncbi.nlm.nih.gov/pubmed/35546357
http://dx.doi.org/10.1038/s42003-022-03395-9

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