Activation of Xist by an evolutionarily conserved function of KDM5C demethylase

XX female and XY male therian mammals equalize X-linked gene expression through the mitotically-stable transcriptional inactivation of one of the two X chromosomes in female somatic cells. Here, we describe an essential function of the X-linked homolog of an ancestral X-Y gene pair, Kdm5c-Kdm5d, in...

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Detalles Bibliográficos
Autores principales: Samanta, Milan Kumar, Gayen, Srimonta, Harris, Clair, Maclary, Emily, Murata-Nakamura, Yumie, Malcore, Rebecca M., Porter, Robert S., Garay, Patricia M., Vallianatos, Christina N., Samollow, Paul B., Iwase, Shigeki, Kalantry, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095838/
https://www.ncbi.nlm.nih.gov/pubmed/35545632
http://dx.doi.org/10.1038/s41467-022-30352-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095838/
https://www.ncbi.nlm.nih.gov/pubmed/35545632
http://dx.doi.org/10.1038/s41467-022-30352-1

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