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High-throughput analysis of ANRIL circRNA isoforms in human pancreatic islets

The antisense non-coding RNA in the INK locus (ANRIL) is a hotspot for genetic variants associated with cardiometabolic disease. We recently found increased ANRIL abundance in human pancreatic islets from donors with certain Type II Diabetes (T2D) risk-SNPs, including a T2D risk-SNP located within A...

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Detalles Bibliográficos
Autores principales: MacMillan, Hannah J., Kong, Yahui, Calvo-Roitberg, Ezequiel, Alonso, Laura C., Pai, Athma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095874/
https://www.ncbi.nlm.nih.gov/pubmed/35546161
http://dx.doi.org/10.1038/s41598-022-11668-w