Gasdermin-A3 pore formation propagates along variable pathways

Gasdermins are main effectors of pyroptosis, an inflammatory form of cell death. Released by proteolysis, the N-terminal gasdermin domain assembles large oligomers to punch lytic pores into the cell membrane. While the endpoint of this reaction, the fully formed pore, has been well characterized, th...

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Detalles Bibliográficos
Autores principales: Mari, Stefania A., Pluhackova, Kristyna, Pipercevic, Joka, Leipner, Matthew, Hiller, Sebastian, Engel, Andreas, Müller, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095878/
https://www.ncbi.nlm.nih.gov/pubmed/35545613
http://dx.doi.org/10.1038/s41467-022-30232-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095878/
https://www.ncbi.nlm.nih.gov/pubmed/35545613
http://dx.doi.org/10.1038/s41467-022-30232-8

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