Improving polygenic prediction with genetically inferred ancestry

Genome-wide association studies (GWASs) have demonstrated that most common diseases have a strong genetic component from many genetic variants each with a small effect size. GWAS summary statistics have allowed the construction of polygenic scores (PGSs) estimating part of the individual risk for co...

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Detalles Bibliográficos
Autores principales: Naret, Olivier, Kutalik, Zoltan, Hodel, Flavia, Xu, Zhi Ming, Marques-Vidal, Pedro, Fellay, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095896/
https://www.ncbi.nlm.nih.gov/pubmed/35571679
http://dx.doi.org/10.1016/j.xhgg.2022.100109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9095896/
https://www.ncbi.nlm.nih.gov/pubmed/35571679
http://dx.doi.org/10.1016/j.xhgg.2022.100109

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