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Muc5b Contributes to Mucus Abnormality in Rat Models of Cystic Fibrosis

Cystic fibrosis (CF) airway disease is characterized by excessive and accumulative mucus in the airways. Mucociliary clearance becomes defective as mucus secretions become hyperconcentrated and viscosity increases. The CFTR-knockout (KO) rat has been previously shown to progressively develop delayed...

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Detalles Bibliográficos
Autores principales: Keith, Johnathan D., Henderson, Alexander G., Fernandez-Petty, Courtney M., Davis, Joy M., Oden, Ashley M., Birket, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096080/
https://www.ncbi.nlm.nih.gov/pubmed/35574458
http://dx.doi.org/10.3389/fphys.2022.884166