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Basal Vascular Smooth Muscle Cell Tone in eNOS Knockout Mice Can Be Reversed by Cyclic Stretch and Is Independent of Age

Introduction and Aims: Endothelial nitric oxide synthase (eNOS) knockout mice develop pronounced cardiovascular disease. In the present study, we describe the alterations in aortic physiology and biomechanics of eNOS knockout and C57Bl/6 control mice at 2–12 months of age, including a thorough physi...

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Detalles Bibliográficos
Autores principales: De Moudt, Sofie, Hendrickx, Jhana O., De Meyer, Guido R. Y., Martinet, Wim, Fransen, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096105/
https://www.ncbi.nlm.nih.gov/pubmed/35574444
http://dx.doi.org/10.3389/fphys.2022.882527