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Sodium-glucose co-transporter 1 (SGLT1) differentially regulates gluconeogenesis and GLP-1 receptor (GLP-1R) expression in different diabetic rats: a preliminary validation of the hypothesis of “SGLT1 bridge” as an indication for “surgical diabetes”

BACKGROUND: Sodium-glucose co-transporter 1 (SGLT1) may play a synergistic role in gluconeogenesis (GNG) and glucagon-like peptide-1 (GLP-1) expression. We proposed the hypothesis of a “SGLT1 bridge” as an indication for “surgical diabetes” that was preliminary validated in the present study. METHOD...

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Detalles Bibliográficos
Autores principales: Zhu, Hengliang, Cai, Huajie, Wang, Xiaokun, Chen, Tao, Zhen, Chaohui, Zhang, Zhenzhan, Ruan, Xiaojiao, Li, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096370/
https://www.ncbi.nlm.nih.gov/pubmed/35571394
http://dx.doi.org/10.21037/atm-22-1769