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Synergistic efficacy of homoharringtonine and venetoclax on acute myeloid leukemia cells and the underlying mechanisms

BACKGROUND: To evaluate whether homoharringtonine (HHT) combined with venetoclax could produce a synergistic anti-acute myeloid leukemia (AML) effect and determine the underlying mechanisms. METHODS: The effect of HHT and venetoclax combination on cell viability, apoptosis, and mitochondrial membran...

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Detalles Bibliográficos
Autores principales: Yuan, Fangfang, Li, Dongbei, Li, Gangping, Cheng, Cheng, Wei, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096386/
https://www.ncbi.nlm.nih.gov/pubmed/35571387
http://dx.doi.org/10.21037/atm-22-1459