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Hyperthermia enhances the efficacy of chemotherapeutic drugs in heat-sensitive cells through interfering with DNA damage repair

BACKGROUND: Hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to be clinically effective, but the mechanisms by which hyperthermia enhances the sensitivity of cells to chemotherapeutic drugs has not yet been elucidated. METHODS: To identify the key molecules involved in thermochemothe...

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Detalles Bibliográficos
Autores principales: Ni, Li-Ping, Sun, Hua-Ting, Wang, Ping, Wang, Juan, Zhou, Jin-Hua, Cao, Ruo-Qi, Yue, Ling, Chen, You-Guo, Shen, Fang-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096405/
https://www.ncbi.nlm.nih.gov/pubmed/35571421
http://dx.doi.org/10.21037/atm-22-955