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Maternal obesity inhibits placental angiogenesis by down-regulating the SIRT1/PGC-1α pathway
BACKGROUND: To explore whether maternal obesity inhibits placental angiogenesis through down-regulation of Sirtuin 1/Peroxisome proliferator-activated receptor-γ coactivator-1α (SIRT1/PGC-1α) signaling pathway. METHODS: In a rat model of pre-pregnancy obesity, rats were sacrificed at embryonic day (...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096407/ https://www.ncbi.nlm.nih.gov/pubmed/35571425 http://dx.doi.org/10.21037/atm-22-1221 |