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Maternal obesity inhibits placental angiogenesis by down-regulating the SIRT1/PGC-1α pathway

BACKGROUND: To explore whether maternal obesity inhibits placental angiogenesis through down-regulation of Sirtuin 1/Peroxisome proliferator-activated receptor-γ coactivator-1α (SIRT1/PGC-1α) signaling pathway. METHODS: In a rat model of pre-pregnancy obesity, rats were sacrificed at embryonic day (...

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Detalles Bibliográficos
Autores principales: Peng, Huilin, Wei, Ming, Huang, Lianjing, Yan, Yaqin, Li, Qing, Li, Sujuan, Wu, Yichi, Gao, Yuan, Xing, Ying, Luo, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096407/
https://www.ncbi.nlm.nih.gov/pubmed/35571425
http://dx.doi.org/10.21037/atm-22-1221