Overexpression of Peroxiredoxin 3 in Cartilage Reduces the Severity of Age‐Related Osteoarthritis But Not Surgically Induced Osteoarthritis in Mice

OBJECTIVE: The study objective was to determine whether overexpression of the mitochondrial antioxidant peroxidase, peroxiredoxin 3 (Prx3), reduces the severity of osteoarthritis (OA) in mice. METHODS: Age‐related OA (age 18 and 24 months) and OA induced by destabilization of the medial meniscus (DM...

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Detalles Bibliográficos
Autores principales: Loeser, Richard F., Coryell, Philip R., Armstrong, Alexandra R., Collins, John A., Gopalakrishnan, Priya, McDermott, Katie A., Ran, Qitao, Carlson, Cathy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096510/
https://www.ncbi.nlm.nih.gov/pubmed/35191223
http://dx.doi.org/10.1002/acr2.11420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096510/
https://www.ncbi.nlm.nih.gov/pubmed/35191223
http://dx.doi.org/10.1002/acr2.11420

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