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Down-Regulation of Insulin Like Growth Factor 1 Involved in Alzheimer's Disease via MAPK, Ras, and FoxO Signaling Pathways

The inability to halt or even delay the course of Alzheimer's disease (AD) forces the development of new molecular signatures and therapeutic strategies. Insulin like growth factor 1 (IGF1) is a promising target for AD treatment, yet exact mechanisms of AD ascribed to IGF1 remain elusive. Herei...

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Detalles Bibliográficos
Autores principales: Kang, Kexin, Bai, Jun, Zhong, Shanshan, Zhang, Rongwei, Zhang, Xiaoqian, Xu, Ying, Zhao, Mei, Zhao, Chuansheng, Zhou, Zhike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096571/
https://www.ncbi.nlm.nih.gov/pubmed/35571248
http://dx.doi.org/10.1155/2022/8169981