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Down-Regulation of Insulin Like Growth Factor 1 Involved in Alzheimer's Disease via MAPK, Ras, and FoxO Signaling Pathways
The inability to halt or even delay the course of Alzheimer's disease (AD) forces the development of new molecular signatures and therapeutic strategies. Insulin like growth factor 1 (IGF1) is a promising target for AD treatment, yet exact mechanisms of AD ascribed to IGF1 remain elusive. Herei...
Autores principales: | Kang, Kexin, Bai, Jun, Zhong, Shanshan, Zhang, Rongwei, Zhang, Xiaoqian, Xu, Ying, Zhao, Mei, Zhao, Chuansheng, Zhou, Zhike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096571/ https://www.ncbi.nlm.nih.gov/pubmed/35571248 http://dx.doi.org/10.1155/2022/8169981 |
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