Physicochemical effect of the N501Y, E484K/Q, K417N/T, L452R and T478K mutations on the SARS-CoV-2 spike protein RBD and its influence on agent fitness and on attributes developed by emerging variants of concern

The spike protein comprises one of the main structural components of SARS-CoV-2 because it is directly involved in the infection process and viral transmission, and also because of its immunogenic properties, as an inducer of the protective antibodies production and as a vaccine component. The occur...

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Detalles Bibliográficos
Autor principal: Pondé, R.A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096574/
https://www.ncbi.nlm.nih.gov/pubmed/35580380
http://dx.doi.org/10.1016/j.virol.2022.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096574/
https://www.ncbi.nlm.nih.gov/pubmed/35580380
http://dx.doi.org/10.1016/j.virol.2022.05.003

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