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Amino acids with fluorescent tetrazine ethers as bioorthogonal handles for peptide modification

A set of 3-bromo-1,2,4,5-tetrazines with three distinct substitutions have been used as reagents for late-stage functionalization of small molecules through nucleophilic aromatic substitution. Spectroscopic studies of the products obtained proved that tetrazine ethers are intrinsically fluorescent....

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Detalles Bibliográficos
Autores principales: Ros, Enric, Bellido, Marina, Matarin, Joan A., Gallen, Albert, Martínez, Manuel, Rodríguez, Laura, Verdaguer, Xavier, Ribas de Pouplana, Lluís, Riera, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096626/
https://www.ncbi.nlm.nih.gov/pubmed/35702248
http://dx.doi.org/10.1039/d2ra02531k