Metformin-induced reductions in tumor growth involves modulation of the gut microbiome()

BACKGROUND/PURPOSE: Type 2 diabetes and obesity increase the risk of developing colorectal cancer. Metformin may reduce colorectal cancer but the mechanisms mediating this effect remain unclear. In mice and humans, a high-fat diet (HFD), obesity and metformin are known to alter the gut microbiome bu...

Descripción completa

Detalles Bibliográficos
Autores principales: Broadfield, Lindsay A., Saigal, Amna, Szamosi, Jake C., Hammill, Joanne A., Bezverbnaya, Ksenia, Wang, Dongdong, Gautam, Jaya, Tsakiridis, Evangelia E., Di Pastena, Fiorella, McNicol, Jamie, Wu, Jianhan, Syed, Saad, Lally, James S.V., Raphenya, Amogelang R., Blouin, Marie-Jose, Pollak, Michael, Sacconi, Andrea, Blandino, Giovanni, McArthur, Andrew G., Schertzer, Jonathan D., Surette, Michael G., Collins, Stephen M., Bramson, Jonathan L., Muti, Paola, Tsakiridis, Theodoros, Steinberg, Gregory R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096669/
https://www.ncbi.nlm.nih.gov/pubmed/35452877
http://dx.doi.org/10.1016/j.molmet.2022.101498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096669/
https://www.ncbi.nlm.nih.gov/pubmed/35452877
http://dx.doi.org/10.1016/j.molmet.2022.101498

Ejemplares similares