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Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells
Myoferlin, an emerging oncoprotein, has been associated with a low survival in several cancer types including pancreas ductal adenocarcinoma where it controls mitochondria structure and respiratory functions. Owing to the high susceptibility of KRAS-mutated cancer cells to iron-dependent cell death,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096673/ https://www.ncbi.nlm.nih.gov/pubmed/35533575 http://dx.doi.org/10.1016/j.redox.2022.102324 |