Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells

Myoferlin, an emerging oncoprotein, has been associated with a low survival in several cancer types including pancreas ductal adenocarcinoma where it controls mitochondria structure and respiratory functions. Owing to the high susceptibility of KRAS-mutated cancer cells to iron-dependent cell death,...

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Detalles Bibliográficos
Autores principales: Rademaker, Gilles, Boumahd, Yasmine, Peiffer, Raphaël, Anania, Sandy, Wissocq, Tom, Liégeois, Maude, Luis, Géraldine, Sounni, Nor Eddine, Agirman, Ferman, Maloujahmoum, Naïma, De Tullio, Pascal, Thiry, Marc, Bellahcène, Akeila, Castronovo, Vincent, Peulen, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096673/
https://www.ncbi.nlm.nih.gov/pubmed/35533575
http://dx.doi.org/10.1016/j.redox.2022.102324

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