Phenotype assessment for neurodegenerative murine models with ataxia and application to Niemann–Pick disease, type C1

Identifying meaningful predictors of therapeutic efficacy from preclinical studies is challenging. However, clinical manifestations occurring in both patients and mammalian models offer significant translational value. Many neurological disorders, including inherited, metabolic Niemann–Pick disease,...

Descripción completa

Detalles Bibliográficos
Autores principales: Yerger, Julia, Cougnoux, Antony C., Abbott, Craig B., Luke, Rachel, Clark, Tannia S., Cawley, Niamh X., Porter, Forbes D., Davidson, Cristin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Methods & Techniques
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096702/
https://www.ncbi.nlm.nih.gov/pubmed/35452076
http://dx.doi.org/10.1242/bio.059052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096702/
https://www.ncbi.nlm.nih.gov/pubmed/35452076
http://dx.doi.org/10.1242/bio.059052

Ejemplares similares