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Generation of an RCVRN-eGFP Reporter hiPSC Line by CRISPR/Cas9 to Monitor Photoreceptor Cell Development and Facilitate the Cell Enrichment for Transplantation

Stem cell-based cell therapies are considered to be promising treatments for retinal disorders with dysfunction or death of photoreceptors. However, the enrichment of human photoreceptors suitable for transplantation has been highly challenging so far. This study aimed to generate a photoreceptor-sp...

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Detalles Bibliográficos
Autores principales: Guan, Yuanyuan, Wang, Yuan, Zheng, Dandan, Xie, Bingbing, Xu, Ping, Gao, Guanjie, Zhong, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096726/
https://www.ncbi.nlm.nih.gov/pubmed/35573687
http://dx.doi.org/10.3389/fcell.2022.870441