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Sialic Acid Derivatization of Fluorescently Labeled N-Glycans Allows Linkage Differentiation by Reversed-Phase Liquid Chromatography–Fluorescence Detection–Mass Spectrometry

[Image: see text] Sialic acids have diverse biological roles, ranging from promoting up to preventing protein and cellular recognition in health and disease. The various functions of these monosaccharides are owed, in part, to linkage variants, and as a result, linkage-specific analysis of sialic ac...

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Detalles Bibliográficos
Autores principales: Moran, Alan B., Gardner, Richard A., Wuhrer, Manfred, Lageveen-Kammeijer, Guinevere S. M., Spencer, Daniel I. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096788/
https://www.ncbi.nlm.nih.gov/pubmed/35482581
http://dx.doi.org/10.1021/acs.analchem.1c02610