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Excess DHA Induces Liver Injury via Lipid Peroxidation and Gut Microbiota-Derived Lipopolysaccharide in Zebrafish

Being highly unsaturated, n-3 long-chain polyunsaturated fatty acids (LC-PUFAs) are prone to lipid peroxidation. In this study, zebrafish were fed with low-fat diet (LFD), high-fat diet (HFD), or 2% DHA-supplemented HFD (HFDHA2.0). To study the possible negative effects of the high level of dietary...

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Detalles Bibliográficos
Autores principales: Ding, Qianwen, Hao, Qiang, Zhang, Qingshuang, Yang, Yalin, Olsen, Rolf Erik, Ringø, Einar, Ran, Chao, Zhang, Zhen, Zhou, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096794/
https://www.ncbi.nlm.nih.gov/pubmed/35571918
http://dx.doi.org/10.3389/fnut.2022.870343