Effect of Methylation of the Hydrophilic Domain of Tocopheryl Ammonium-Based Lipids on their Nucleic Acid Delivery Properties

[Image: see text] Lipid-enabled nucleic acid delivery has garnered tremendous attention in recent times. Tocopherol among the cationic lipids, 3b-[N-(N′,N′-dimethylamino-ethane)carbamoyl]-cholesterol hydrochloride (DC-Chol) with a headgroup of dimethylammonium, and cholesterol as a hydrophobic moiet...

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Detalles Bibliográficos
Autores principales: Rapaka, Hithavani, Manturthi, Shireesha, Gosangi, Mallikarjun, Lohchania, Brijesh, Marepally, Srujan, Patri, Srilakshmi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096827/
https://www.ncbi.nlm.nih.gov/pubmed/35571792
http://dx.doi.org/10.1021/acsomega.1c06889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096827/
https://www.ncbi.nlm.nih.gov/pubmed/35571792
http://dx.doi.org/10.1021/acsomega.1c06889

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