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Effect of Methylation of the Hydrophilic Domain of Tocopheryl Ammonium-Based Lipids on their Nucleic Acid Delivery Properties
[Image: see text] Lipid-enabled nucleic acid delivery has garnered tremendous attention in recent times. Tocopherol among the cationic lipids, 3b-[N-(N′,N′-dimethylamino-ethane)carbamoyl]-cholesterol hydrochloride (DC-Chol) with a headgroup of dimethylammonium, and cholesterol as a hydrophobic moiet...
Autores principales: | Rapaka, Hithavani, Manturthi, Shireesha, Gosangi, Mallikarjun, Lohchania, Brijesh, Marepally, Srujan, Patri, Srilakshmi V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096827/ https://www.ncbi.nlm.nih.gov/pubmed/35571792 http://dx.doi.org/10.1021/acsomega.1c06889 |
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